what is igf-1 lr3 Recombinant Human IGF-I/IGF-1 GMP Protein, CF 8335D-GMP: R&D Systems IGF-1 LR3 PEPTIDE 1MG/10MG VIAL

ROS induces endothelial dysfunction, decreases vasodilator and increases contractile factors, and damages cell structures, causing atherosclerosis, heart failure, hepatic steatosis, and cancer

Neither compound has published the kind of long-term hard-outcome data (cardiovascular events, mortality) that ultimately defines a metabolic drugs value, because both are too early in development for that

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PloS One (2017) 12(8):e0182835

Those are two different things, and I'd rather you know that upfront than find out after three months