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From the bile, they come into the intestine where enzyme glucuronidase is present which hydrolyses the conjugate and the active drug is reabsorbed from the small intestine into the systemic circulation and the process is called enterohepatic circulation [11]
Therefore, parenteral cyanocobalamin should be administered to a pregnant woman if the benefits outweigh the risks (10, 11)
With persistent hypoxia, HIF-1 remains activated and drives abnormal expression of downstream genes, including heme oxygenase-1 ( H O -1 ) (Zhai et al., 2023)
Lyophilized: Store at 20 C (4 F) in dry, dark conditions
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