They demonstrated that human pancreatic tumor and stellate cells activate/process GSAO into its active metabolite and that GT activity positively correlates with GSAO-mediated proliferation arrest of co-cultured endothelial cells ( Figure 3B )
Yu MH, Lee JM, Baek JH, Han JK, Choi BI
Napolitano et al., 2014
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The higher dose of 0.14 mol/kg had even greater effects, with less than 25% of radioactivity remaining in the stomach after 15 minutes
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