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24, 39, 40, 268, 269 A key issue for future clinical trial design will be to identify clinically relevant objective criteria for patient enrollment, and this remains a challenge, which has delayed a more aggressive approach of the pharmaceutical industry to identifying new treatment avenues for this condition
Diehl, F
10.1093/toxsci/kfu040 Toxicol Sci
It featured in a small combination trial with saw palmetto that showed 60% improvement versus placebo, though you cannot separate which ingredient did the work
It can act on enterocytes and underlying tissue directly from the luminal side
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