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In conclusion, several studies have demonstrated that FFAs are more likely to lead to tumor resistance by promoting FAO under obese conditions, and that PPAR, as a common regulator of FAO and adipocytes, has great potential in tumor therapy

Opioid use may worsen gastric retention Higher prevalence of recent opioid use in the high RGC group Suggests an additive effect on gastric motility No difference in indication or duration of therapy Whether patients used GLP-1 RAs for diabetes or weight loss did not affect risk Duration of therapy was not a significant predictor Interpretation Withholding 7.5 days higher risk of retained gastric contents Fasting 21.3 hours strongest predictor of high RGC These thresholds optimize sensitivity and specificity for detecting risk

Phentermine may suit individuals who respond poorly to GLP-1 side effects