(2021) Once-weekly semaglutide in adults with overweight or obesity, New England Journal of Medicine
GLP-1RAs, including semaglutide, liraglutide, and tirzepatide, are now a central part of obesity treatment
These medications are not routinely prescribed and require hepatology input in line with NICE guidance
Back Phelan, M (30 May 2024) 'Winning researchers unlocked GLP-1 drugs for obesity', Science , 384/6699
With a 17 mg/mL vial, 5 mg 29 units
[24] Finally, a 2020 Cochrane systematic review found insufficient evidence to suggest that metformin monotherapy reduced all-cause mortality, serious adverse events, cardiovascular mortality, non-fatal myocardial infarction, non-fatal stroke, or end-stage renal disease when compared to DPP-4 inhibitors for the treatment of type 2 diabetes