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This slower rate of gastric emptying aids in better blood sugar control and promotes a feeling of fullness, contributing to its weight management benefits

Inhibition of cholesterol esterification in T cells by genetic ablation or pharmacological inhibition of ACAT1 (a key cholesterol esterase) can lead to potentiated effector function and enhanced proliferation of CD8(+) T cells by increasing plasma membrane cholesterol levels, which causes enhanced T-cell receptor clustering and signaling as well as more efficient formation of the immunological synapse, thereby controlling the growth and metastasis of mouse melanoma (284)

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Analyses of renal biopsies obtained from T2D patients support a multifactorial pathophysiology as the structural damage observed varies

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