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For most people it is mild to moderate and improves over the following weeks
Weight loss in men can improve sperm quality and in at least one report, improved fertility after liraglutide-induced weight loss was documented
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NHS prescribing requires a separate NICE technology appraisal
They offered efficacy that patients and clinicians could not ignore, meaningful cardiometabolic benefits, and a safety profile dominated by manageable gastrointestinal side effects rather than catastrophic risks
Similarly, cardiovascular benefits independent of GLP-1R activation have also been demonstrated [38]
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