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These conditions include aging and age-associated chronic muscle conditions such as cachexia 248 , sarcopenia 124,249,250 , inclusion body myositis (IBM) 114,251,252 , and neuromuscular diseases like Duchennes muscular dystrophy (DMD) 253,254

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Retatrutide, because it activates three receptor pathways at once, may cause more gastrointestinal discomfort at higher doses

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