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too much self-renewal would result in germline tumors of proliferating cells and a reduction or elimination of differentiated gametes that are formed, while too much differentiation would result in the GSC population being depleted and a lack of sustained gamete formation

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But we don't make up stuff. On Sept

Oral supplements are effective for mild deficiency and maintenance

Injections of B12 work rapidly and are the most effective way to treat a deficiency