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Vitamin E, pentoxifylline, and potassium para-aminobenzoate (Potaba) have shown modest benefits in some studies

Anti-drug antibodies may develop against therapeutic peptides, particularly those that differ structurally from endogenous human peptides

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Neither has completed comprehensive Phase 3 safety trials for tissue healing, so long-term human safety data remains limited for both

For those of you interested exclusively in the nonprescription topicals, we recommend checking out our guide to the best copper peptide serum