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Current data shows 40% of US adults live with obesity, more than 100 million potential users, yet demand for these medications remains high despite substantial costs

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Gradual dose escalation (starting low and increasing slowly) is the most effective prevention strategy

Moreover, the cell proliferation ability of HCC cell lines (MHCC97H and HepG2) and PCa cell lines (LNCaP and C4-2) increased with an increase in Gln concentration, as determined by cell CCK- 8 and colony formation assays (Fig