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In our experimental condition, the SI 75 of CPP-CAND demonstrated significant superiority compared to FOXO4-DRI, with an approximately-1.2 fold higher selectivity, despite its shorter length

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Based on Phase 2 data, retatrutide's side effect profile is consistent with the GLP-1 class: nausea, vomiting, diarrhea, and constipation, most prominent during dose escalation and typically resolving over time