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Other than direct consequences, such as degenerative arthritis and sleep apnea, its controversial whether being overweight in and of itself causes a health risk
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3 Discussion To our knowledge, this is the second reported case implicating tirzepatide as a causative agent for rhabdomyolysis
In APP/PS1 transgenic mice, (D-Ser2)Oxm, a dual GLP-1 and Gcg receptor agonist, notably improves spatial memory and synaptic plasticity, reduces A plaque deposition in the hippocampus, and modulates the PI3K/AKT1/GSK3 signaling pathway [84]
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