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Pain scores also improved substantially: retatrutide reduced Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) pain scores by as much as 4.5 points (75.8%), compared with a 2.4-point (40.3%) reduction with placebo

After taking the late dose, you can either return to your original scheduled day the following week or make the new day your permanent injection day, as long as there are at least 48 hours between the doses

Gallbladder-related events, including cholelithiasis and cholecystitis, occur more frequently with GLP-1 therapy, likely related to rapid weight loss rather than direct drug effects

If the pen exceeded 86F or has been in use more than 56 days, discard

Review the package insert for each medication

Maximum savings caps or time limits can raise the cost later in the weight loss journey