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These drugs can lead to significant weight loss, around 10% of body weight within six months, but may also cause side effects
Aggregates form when peptides unfold and bind to each other through exposed hydrophobic regions, creating insoluble clumps that cannot interact with melanocortin receptors
In 2014, the European Medicines Agency (EMA) approved afamelanotide (Scenesse) for the treatment of EPP, making it the first melanocortin receptor agonist to receive regulatory approval for a medical condition
Cardiovascular disease (CVD): Obesity fuels up to 78% of hypertension cases, contributing to CVDs $320 billion yearly burden in the U.S
Almost all individuals will see at least 5% total body weight reduction on these types of medications. Stolte said the medication helps the body absorb and store insulin, slows the movement of food through a person's gastrointestinal (GI) tract, and reduces food noise
Store at -20C, protected from light and moisture, for long-term stability
