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Six normal subjects injected with 25 nmol/kg DSIP once in the morning showed a significant increase in total sleep for the next 2 hours (median increase of 59%)

Patients should be counselled on strategies to minimise gastrointestinal symptoms, such as eating smaller meals, avoiding high-fat foods, and staying well-hydrated

Taking care of your guts microbiome with probiotics helps support a healthy digestive system

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sUA and MSU crystals regulate monocyte MSU crystals induce monocyte-associated inflammation.MSU crystals directly instigate the assembly of NLRP3 inflammasome in monocytes, leading to an increase in IL-1 production ( via nuclear factor kappa-B(NF-B)/NLRP3/gasdermin D(GSDMD) signaling pathway activation

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