Se can reduce the incidence rate of heart disease in humans, but ROS formed during oxidative stress can initiate lipid peroxidation, damage normal cell function, and lead to myocardial ischemia reperfusion (I/R) injury
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In pharmacologic doses (50100 grams or more), vitamin C acts as a pro-oxidant , selectively generating hydrogen peroxide in the extracellular space, which may damage tumor cells while sparing healthy cells
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An early study showed that 250 M acetyl-l-carnitine did not affect axon regeneration but significantly reduced the rate of death of neurons from the DRG of aging rats, suggesting its neuroprotective action [14]