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While missing one weekly dose of a GLP-1 or GIP/GLP-1 receptor agonist is generally not medically dangerous, prolonged interruption can lead to return of appetite, potential weight regain, and in patients with type 2 diabetes, deterioration of glycemic control

The novel dual glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 (GLP -1) receptor agonist tirzepatide transiently delays gastric emptying similarly to selective long-acting GLP -1 receptor agonists

Patients taking Zepbound should maintain open communication with their healthcare provider regarding gastrointestinal symptoms and any anorectal concerns

The affected area typically measures 1 to 3 centimeters in diameter and feels warm to the touch

Certain bariatric surgeries might be better suited for these individuals, she says, but retatrutide could be part of the conversation

Research-Use Dosing Conventions (Not a Recommendation) This section describes the dose ranges used inside clinical trials and laboratory research settings only