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The cost-effectiveness analysis of semaglutide for the treatment of adult and adolescent patients with overweight and obesity: a systematic review

Age, baseline metabolic health, and concurrent medications can also affect tolerance

Ozempic, for instance, was being used off-label quite often

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According to the Wegovy SmPC, treatment should be reviewed after 6 months at the maintenance dose (2.4 mg or maximum tolerated dose)

This personalization can improve outcomes and reduce costly trial-and-error switching