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Retatrutide activates three receptors - GLP-1, GIP and glucagon - producing stronger metabolic and anti-inflammatory effects than current GLP-1 medications
Oral supplements, on the other hand, are more convenient but may take longer to produce visible results due to lower absorption rates
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After 36 weeks, the 0.5 mg retatrutide group showed a 3.19% body weight reduction, the 4 mg group showed a 10.37% decrease, the 8 and 12 mg groups demonstrated decreases of 16.81% and 16.94% respectively, which were significantly greater than those observed with placebo (3.00%) and 1.5 mg dulaglutide (2.02%) [114]
Drucker DJ (2024) Efficacy and safety of GLP-1 medicines for type 2 diabetes and obesity
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