More clinical evidence can be found on the role of GLP1R agonists such as exenatide can improve vascular endothelial dysfunction in diabetic patients, as has been found in this clinical trial by Hu et al., results suggested that exenatide improved the endothelial dysfunction reflected by digital reactive hyperemia index in newly diagnosed patients with T2DM, and the effect was not inferior to single metformin [59]
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Tingling that resembles the "pins and needles" of a limb falling asleep, but without an obvious cause
Conversely, other studies have found positive benefits with normal breakfast or lunch scenarios
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