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Strategies to modulate ROS levels include the use of antioxidants, ROS scavengers, and inhibitors of ROS-generating enzymes

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Deciphering the reversible glutaredoxin-dependent redox reactions of roGFP2 therefore not only closes a gap in our knowledge of glutaredoxin catalysis but also facilitates the intrepretation of roGFP2 responses from redox measurements and mechanistic analyses in vivo

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