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9 During pathological states, reaction between nitric oxide and superoxide can generate highly reactive peroxynitrite (ONOO-) radicals, which are implicated in lipid peroxidation
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The Neo-AEGIS trial reported comparable clinical outcomes between the two approaches in terms of survival benefit and quality-of-life metrics
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In parallel, steroid hormone secretion by granulosa cells is known to be closely associated with membrane lipid metabolism, particularly with respect to the proper localization and functional activity of key steroidogenic proteins such as StAR and CYP11A1, which are highly dependent on the membrane microenvironment [82]
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