Apurinic/Apyrimidinic (AP) sites in the brain, spinal cord, and brainstem of ALS patients are vulnerable to DNA lesions induced by free radicals and intermediates (Kim et al., 2020)
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In addition, chloroquine has been described to compete with NADH for binding to glycolytic enzyme lactate dehydrogenase, occupying the NADH-binding pocket of this enzyme, which was illustrated in the malarial parasite Plasmodium falciparum [101]
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The table is scientific and comparative in nature and does not constitute a direct head-to-head comparison or a claim about the effect of the research-grade product