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After the impact, the influx of Ca 2+ ions into the cell cytoplasm leads to the phosphorylation/activation of phospholipases that cleave phospholipids into fatty acids, diaglycerols and lysophospholipids like LPC, which initiates signaling cascades that drive inflammation, BBB destruction, demyelination, and protein aggregation in several neurodegenerative contexts [81]
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Front Aging Neurosci:14
Enhanced antioxidant protection: Glutathione helps neutralize free radicals and decrease oxidative stress, protecting the cells from damage and supporting overall health
In addition to cytoskeletal proteins, enzymes involved in sperm metabolism and energy production are also affected by oxidative stress (75, 76)
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