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Repeated freeze-thaw cycling is one of the more common causes of peptide degradation, since the formation and melting of ice crystals can physically disrupt peptide bonds with each cycle

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Holland D, Ben-Hayyim G, Faltin Z, Camoin L, Strosberg AD, Eshdat Y (1993) Molecular characterization of salt-stress-associated protein in citrus: protein and cDNA sequence homology to mammalian glutathione peroxidases

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(c) Ultrasound vocalizations (USVs) were recorded during interactions with the male test mouse in the presence of an unfamiliar female in estrous