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Changes in regulatory enforcement could affect availability and pricing, potentially making compounded options more expensive or less accessible in the future

Peer review Peer review information Nature Medicine thanks Qiwei Li, Carel le Roux and Katherine Tuttle for their contribution to the peer review of this work

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Ketosis , which can occur during significant weight loss or reduced carbohydrate intake, may also produce a characteristic fruity or acetone-like breath odour

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