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Despite the valuable insights gained from this scoping review, several limitations should be acknowledged

More of those on the 3 mg dose lost 5% or more of their total body weight than those on the placebo

For this secondary report, we estimated that the study would have at least 80% power to detect differences between groups in physical functional performance (0.8 s in the stair climb test), cardiorespiratory fitness (3.0 mL/min/kg FFM), and muscle strength (15 Nm)

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We cannot supplement our way out of a bad diet and lifestyle

Where the safeguards sit along the route Because the route touches two jurisdictions, it is fair to ask where the protections are, and the honest answer is that there is a named, accountable regulator at every link