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The most common and well known side effects include nausea, vomiting, constipation, and diarrhoea, which occur in up to 40% of people taking GLP-1 drugs.3 These side effects can make more than one in 10 patients interrupt treatment.4 Patients sometimes attribute loss of appetite due to nausea as part of the mechanism for initial weight loss and are willing to Log in Log in using your username and password Log in through your institution Subscribe from 184 * Subscribe and get access to all BMJ articles, and much more
Neither medication is a magic pill
Some experience side effects due to a deficiency in processing nutrients, making it important to monitor glutathione intake
GIP has been shown to decrease food intake while blunting the metabolic adaptive responses that usually occur with calorie restriction resulting in weight reductions, and when combined with GLP-1 receptor agonism, may result in greater effects on markers of metabolic dysregulation such as body weight, glucose and lipids
Most patients on a properly structured 36 month protocol notice meaningful changes in body composition, not just the scale
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