As anticipated, the dissection of apparent equilibria into elementary redox ones in biological thiol-disulfide systems reveals significant differences between reactions of apparently highly similar, covalently identical reactants, improving thus our understanding of redox homeostasis and providing new means to influence it
Similarly, genes associated with mitochondrial activity, including components of the respiratory chain and TCA cycle, are downregulated, leading to decreased ATP production and impaired redox balance [41,42,43,44,45,46]
Immune-based therapy in triple-negative breast cancer: from molecular biology to clinical practice
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