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Fromenty B, Roden M
Berberine is a plant-based supplement that's gained a lot of traction on social media as a "natural" way to support blood sugar and metabolic health sometimes even called "nature's Ozempic." But pairing it with a GLP-1 can be risky
Estimation of the global prevalence of dementia in 2019 and forecasted prevalence in 2050: an analysis for the global burden of disease study 2019
Step 1: Dietary and lifestyle changes Increase soluble fiber gradually to 25-30 grams per day (psyllium husk, oats, chia seeds, ground flaxseed) Drink 64-80 oz of water daily, spread throughout the day Add prunes or prune juice (4-6 prunes or 4-8 oz juice daily) Increase physical activity, especially walking (stimulates colonic motility) Establish a consistent bathroom routine (same time each day, usually 20-30 minutes after breakfast) About 40% of patients with mild GLP-1 constipation see improvement within 7-10 days of consistent dietary changes alone
Avoid repeated freeze-thaw cycles, as these degrade peptide structure and potency