This is one of the first peptide-based therapies for disc disease to reach human clinical trials, and its outcomes will significantly influence the field
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In contrast, Nrf2 activators, such as sulforaphane, have been found to prevent homocysteine- or hydrogen peroxide-induced cataract formation in human lens epithelial cells by increasing nuclear translocation of Nrf2 and expressions of cellular antioxidants, including catalase, superoxide dismutase, glutathione peroxidase, and glutathione
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These variables contribute to the model's explanatory power, as reflected in their relatively large mean squares and F-values