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Since TFR1 mediates the main route of iron entry into neurons via the Tf-TFR1 complex, HIF-1-dependent TFR1 induction leads to iron influx and overload within neurons (134)
In an interview, Lurie said allowing peptides on the market without clinical testing poses a "profound threat" to FDA's decades-old system for vetting drugs
Lancet 406(10499):135148
10.1186/s12951-022-01477-8 190
3B and Supplementary Fig
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