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Metformin, a diabetes drug, alters the gut microbiome and increases SCFAs and bile acids that activate GLP-1, which has led to exploration of metformin in AD and PD trials for its possible MGBA benefits [278, 279]
The arginate salt form is a newer formulation designed for greater stability, particularly in liquid form and in the harsh environment of the GI tract
de Groot, and E
& Paull, T
That detail becomes important later
\n\n\n\n It is critical to note, however, that preclinical safety data no matter how consistently positive cannot be directly extrapolated to humans without proper clinical trials
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