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Mechanisms of action and therapeutic applications of GLP-1 and dual GIP/GLP-1 receptor agonists
User reports suggest 2-5 pounds over 4-8 weeks, though these results cannot be separated from concurrent dietary and exercise changes
reduced GABA signaling is linked to heightened anxiety Serotonin and dopamine influence mood regulation and motivation Glutamate drives excitatory signaling that, in excess, can fuel overactive stress circuits Chronic stress can also trigger low-grade neuroinflammation, a process increasingly tied to both anxiety and depression in clinical studies
Clinical data shows improvements in sleep quality, faster sleep onset, and more REM at 50 to 300mg daily
Gano, L
Archived from the original on January 11, 2017
