It works by supporting tissue repair, which takes time
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- Business segments Merck and Co
In a number of studies, GLP-1R agonists such as liraglutide, exenatide and lixisenatide can reduce neuroinflammation in AD models, thereby improving cognitive dysfunction (140, 141, 144148)
The broader global TRIUMPH clinical development program began in 2023 and has enrolled more than 5,800 participants across four registrational Phase 3 trials
Examples of drugs that are in the latter class include the anti-malarial drugs dapsone and primaquine, as well as rasburicase which is normally used in the treatment tumor lysis syndrome in patients undergoing chemotherapy for hematologic cancers, but has also been used to reduce the hyperuricemia associated with gout