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Given the convenience of a once-daily injection compared to several daily injections, long-acting amylin agonists are attractive to develop and are currently being pursued as novel anti-obesity and anti-diabetes drug candidates by multiple pharmaceutical companies

This novel feature of TNBS to wear off GSH, coupled with its potential for ROS generation, demonstrates that TNBS promotes two independent mechanisms of injury, namely, GSH limitation and ROS accumulation, which in cooperation trigger a chain of processes that lead to cell damage

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Resting metabolic rate on the PNO platform