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In biochemical and preclinical models, the peptide appears to regulate endothelial activity, cell migration, and cytoskeletal organization through interactions with kinase signaling cascades and nitric oxide related mechanisms
doi: 10.1126/scitranslmed.aat3392 55 HeimbrgerSMBergmannNCAugustinRGasbjergLSChristensenMBKnopFK
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There are arguments against the use of oral cobalamin in initiation of cobalamin therapy in severely deficient individuals who have poor absorption, especially due to pernicious anaemia
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