In particular, the combination of no hypoglycemia and weight loss in most patients (rather than weight gain, as is commonly seen with insulin and TZDs), have made this class very appealing to doctors and healthcare educators (see the Learning Curve in diaTribe #24 for more details)
What's particularly fascinating is the timing patients experience noticeable improvements in their most troublesome symptoms within 2-4 weeks of starting low-dose GLP-1 therapy, much faster than traditional MCAS treatments that can take months to show benefit
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Understanding GLP-1 and Its Natural Role To understand GLP-1 agonists, we first need to explore GLP-1 itself
Limit: Hot peppers and hot sauces Heavily spiced curries Spicy Mexican or Thai dishes Foods with excessive black pepper or cayenne Refined Carbohydrates and Sugary Foods These foods provide little nutritional value and can worsen blood sugar fluctuations and digestive discomfort
One in eight US adults have already taken GLP-1 drugs for weight loss or blood sugar control, and the figure is predicted to rise to up to one in six in the future