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The mechanism is not well established it may relate to individual sensitivity, dehydration coinciding with supplement use, or other unrelated factors

It is important to note that serum Se (S-Se) does not directly reflect the concentration of Se in tissues, and even normal S-Se content does not exclude the possibility of Se deficiency in the thyroid (119, 120)

PubMed Sigalos JT, Pastuszak AW

S8), suggesting that BSO may delay tumor initiation rather than tumor expansion

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The demographic and clinical data of the patients are shown in Table 1