Studies demonstrate the peptide reduces neuronal death in cell culture models of oxidative stress and glutamate excitotoxicity, with protective effects observed at the same ultralow concentrations that produce cognitive enhancement
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It is also important to remember that existing studies vary in quality and scope
DNA Repair When DNA is exposed to ROS, it induces an oxidative base modification that could result in transcriptional mutagenesis (Lindahl, 1993), two processes that leads to genomic instability and cell death (Rodier et al., 2009)
Oxidative stress biomarkers (8-isoprostane) decreased by 35%