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This review explores the molecular mechanisms underlying early DR, including microvascular damage, inflammation, oxidative stress, and advanced glycation end products, with distinct profiles in type 1 and type 2 diabetes

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doi: 10.3389/fpls.2017.01720 38 KoramutlaM

Luminescence was measured using the Nivo plate reader (PerkinElmer)

In this population: Higher waist-to-hip ratio increased risk up to 7.7-fold (especially peri-menopausally) Greater body fat percentage, waist-height ratio, or visceral fat area each increased risk around 4-fold Higher body mass index (BMI) or waist circumference, each, increased risk almost 3-fold Because obesity is associated with significant changes in immunometabolic and hormonal parameters, it seems likely that the strength of these findings will be confirmed in other populations

Glutathione metabolism in type 2 diabetes and its role in oxidative stress