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This continuous bombardment by mycotoxins keeps mast cells in a chronic state of hyper-reactivity

These include improving vascular function, reducing systemic inflammation, enhancing coronary microvascular function, and mitigating comorbid conditions like metabolic dysfunction-associated steatotic liver disease (MASLD) and chronic kidney disease (CKD)

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Glutamatergic excitotoxicity contributes to neuroinflammation and hippocampal atrophy, heightening MDD vulnerability

Their operational definitions are detailed in Additional file 1: Table S4

Both GHK-Cu and Epithalon have strong safety profiles and are generally well tolerated