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Four weeks of weekly doses at 2.5mg fits perfectly within that window

J Intern Med 290(2):257278 Demase K, Monitto CK, Little RD, Sparrow MP (2023) The role of low-dose oral methotrexate in increasing anti-TNF drug levels and reducing immunogenicity in IBD

D., Karwi, Q

Furthermore, the generalizability of our results to certain high-risk populations, such as individuals with advanced CKD or those with HF with reduced EF, remains uncertain due to underrepresentation of these subgroups in the included trials