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Lixisenatide for type 2 diabetes mellitus patients inadequately controlled on oral antidiabetic drugs: a mixed-treatment comparison meta-analysis and cost-utility analysis

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11 Patients likely to benefit from these medicines who do not meet the criteria for funded treatment are those: 11 With CVD (or five-year CVD risk 15%), renal disease or heart failure * with a HbA 1c 75 mmol/mol do not usually require a reduction in insulin or sulfonylurea, unless they have a history of hypoglycaemia

Then came tirzepatide, which mimicked two (GLP-1 plus glucose-dependent insulinotropic polypeptide, or GIP)

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