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Plasmids of wildtype and mutants of ARE motifs were transfected to K562 (#CRL-3344, ATCC), an erythroleukemia cell, along with pDsRed1-N1 (PT3405, Clontech), which is used as a transfection efficacy control
46 OKaneR
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Not only did both groups show significant improvements in bilirubin levels (a substance made in the liver during the normal process of breaking down red blood cells that a healthy liver regularly eliminates) months after the trial ended, they also saw a reduction of malondialdehyde, a marker of cell damage in the liver
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Tschopp, J
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