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This is one clear Vitamin B12 benefit people notice when their levels improve

This represents a statistically significant drop

NNMT is an enzyme that methylates nicotinamide (a form of vitamin B3), converting it to N1-methylnicotinamide and effectively removing it from the NAD+ salvage pathway

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Luka Z, Pakhomova S, Loukachevitch LV, Calcutt MW, Newcomer ME, Wagner C

Methylcobalamin injections are administered by licensed clinicians using medical grade protocols and are generally well tolerated