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These drugs are known as glucagon-like peptide-1 (GLP-1) receptor agonists, and they work by mimicking the naturally occurring GLP-1 hormone in the gut

The API is the peptide itself, but the drug product is the final form that the patient uses, which for most GLP-1s, is a sophisticated autoinjector pen

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were often deficient in nutrients

During 1,414,144 person-years of follow-up, cholangiocarcinoma occurred among 222 patients with use of DPP4 inhibitors (incidence rate, 26 per 100,000 patient-years) and among 128 patients with use of sulfonylureas (incidence rate, 23 per 100,000 patient-years)

Additionally, these gastrointestinal conditions could be fatal if patients do not receive proper medical attention