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Your body may recognize it as foreign and mount a small allergic type response

Tirzepatide takes approximately 25 days (3-4 weeks) to be substantially eliminated from your system after your final injection

Eur J Biochem (1993) 214:82935

Efficacy and safety of co-administered once-weekly cagrilintide 24 mg with once-weekly semaglutide 24 mg in type 2 diabetes: a multicentre, randomised, double-blind, active-controlled, phase 2 trial